Wang Zhen, Department of Dermatology, Shenyang Seventh People’s Hospital: Do you have joint pain? Suggest you check blood routine, urine routine, blood sedimentation, ANA, dsDNA,ENA, complement patient: description of the condition (onset time, main symptoms, hospital visited, etc.): The patient is male, 39 years old, previously in good health. This time the condition, the body is afraid of cold and wind, fatigue, after the summer wind, the body will get large eczema, and now the body is getting thinner and thinner. He has been taking medication but not getting better. 1 You see whether it is serious or not?