Thyroid nodules category 2, that is, category 2 of the TI-RADS classification of thyroid ultrasonography, are benign nodules that generally require no specific treatment. Surgery may be an option if the nodule is causing compression symptoms or cosmetic problems; if combined with hyperthyroidism or hypothyroidism, it may be treated with appropriate medications. TI-RADS is a thyroid nodule ultrasound malignancy risk stratification that relies on a number of ultrasound features of thyroid nodules to grade the degree of malignancy risk of the nodules and guide clinical diagnosis and treatment. Thyroid nodules TI-RADS category 2 are benign nodules with a malignancy rate of approximately zero. For benign thyroid nodules, no specific treatment is usually required and regular follow-up reviews are performed. If the nodules cause compression symptoms or cosmetic problems, surgery may be an option. If combined with abnormal thyroid function, hyperthyroidism can be treated with antithyroid medication, and hypothyroidism can be treated with medication such as levothyroxine. When thyroid nodules appear, it is recommended to seek timely medical treatment and standardize the treatment under the guidance of professional doctors.