Hormones used to reduce fever are generally corticosteroids, such as dexamethasone, hydrocortisone, etc., playing such hormones to reduce fever has certain side effects, the emergence of side effects with the course of the dose, the underlying disease, liver and kidney function. Clinically some difficult to control high fever adult STILL disease, etc., manifested as high fever, in the exclusion of tuberculosis, may use hormones, as long as the drug in the normal dose range, short-term there will be no obvious side effects. But the course of the disease is lingering, the application of too much for too long most of the hormone adverse reactions, such as full moon face, gastrointestinal reactions, elevated blood sugar and so on. It is necessary to be given by a physician to treat the symptoms. If the patient himself has tuberculosis, gastrointestinal ulcers, diabetes, mental disorders, blood elevation, etc. If the hormone fever will aggravate the original disease, the proliferation of tuberculosis, abdominal pain, gastrointestinal bleeding, elevated blood glucose, hallucinations, headaches, etc. difficult to control. This is the time to have the underlying disease treated by a physician. Corticosteroids to reduce fever have side effects, the size of which varies from person to person, and need to be applied under the supervision of a physician.