Vulvovaginal leukoplakia is clinically referred to as vulvar leukoplakia. Women with vulvar leukoplakia do not necessarily get cancer, and the severity of the disease has a certain relationship. Female vulvar leukoplakia may be caused by immune abnormality or changes in estrogen in the body, while vulvar leukoplakia has a certain risk of cancer, and it is clinically found that a small portion of women will have malignant changes, so not all women with vulvar leukoplakia will get cancer. If the disease is only in the early stage, the localized white patches are slight, and there is no hardening, and the disease is treated in time, it is usually not cancerous. If the disease is not treated in time, and the condition continues to aggravate, causing localized hardening, and the lesions continue to expand, it will lead to a higher risk of cancer, and if the disease is not controlled in time, it may become cancerous.