Drowned neck is also known as intertrigo rash. The phenomenon of intertrigo rash in newborns is an option when there is no visible skin breakdown, and the use of a glyburide lotion is an option. Interfollicular rash often occurs in the folded areas of the skin due to warmth, moisture, friction and other irritants, resulting in superficial inflammation, which is more common clinically. The main symptoms are erythema, vesicles and exudation, etc. The local skin should be kept clean and dry, and appropriate medication should be given. In the early stage of the lesion, local erythema and no obvious skin breakage, can follow the doctor’s instructions, discretionary topical glycerine lotion, can play the role of itching and astringent, keep the local skin dry to reduce friction, but also to avoid soap, hot water and other undesirable stimuli. With the development of the disease, there may be vesicles, oozing, need to choose the boric acid solution cold wet compress treatment, to be dry after the application of Dinaid cream and other weak glucocorticoid treatment. Newborns appear between the friction rash, should be timely consultation, the above drugs, should be used in strict compliance with the doctor’s instructions, to avoid blind use of drugs and adverse effects.