Skin eczema ulcers and oozing can be dealt with mainly by medication and general treatment. Eczema is an inflammation of the superficial dermis and epidermis caused by a variety of internal and external factors, clinically acute lesions are dominated by herpes papules with a tendency to ooze, and the chronic phase is dominated by mossy changes. The pathogenesis is not clear, and is currently considered to be the result of a combination of internal and external factors based on internal factors such as abnormal immune function and skin barrier dysfunction. Patients with eczema should avoid scratching. If the lesion exudes a lot of people, can be used externally 3% boric acid solution or 0.1% isacridine solution and other cold wet compresses; if there are vesicles, but not much exudate, can be used externally zinc oxide oil and so on. At the same time can follow the doctor’s instructions oral antihistamine drug treatment, such as loratadine, cetirizine, etc.. During the period of medication, it is necessary to reduce external stimuli, such as hot water scalding, violent scratching, excessive wiping, avoid eating irritating food, such as fish and shrimp, strong tea, alcohol, coffee, etc.. It is recommended that eczema patients with skin ulceration and oozing should consult a doctor in time, under the guidance of the doctor’s standardized treatment, and the use of medication should be strictly in accordance with the doctor’s instructions.