Mild interstitial changes in both lungs is an imaging diagnosis that refers to the presence of lesions in the interstitium of the lungs, with the possibility of involvement of the alveoli and pulmonary vasculature, among others. The cause of the disease needs to be further clarified in order to determine the condition. 1. The cause of mild interstitial changes in both lungs is still unclear. Known causes such as asbestosis and pneumoconiosis are related to inhalation of hazardous dust; hypersensitivity pneumonitis is related to inhalation of allergic substances; and the cause of idiopathic pulmonary fibrosis is still unclear. 2. Mild interstitial changes usually have no obvious symptoms, but in severe cases, dyspnea and cough may occur: mostly persistent dry cough, rarely hemoptysis, chest pain and wheezing. 3. The disease is mainly treated by etiologic treatment, symptomatic treatment, and regular follow-up and review. Symptoms need to go to the hospital for detailed examination in time to avoid delayed treatment.