Painful touch on the outer side of the little toe can be given general treatment, medication, physical therapy and surgery according to the cause, which may be related to local soft tissue hyperplasia, onychomycosis, trauma and so on. 1. Local soft tissue hyperplasia: local soft tissue hyperplasia caused by extrusion or chronic wear and tear can form hard knots, resulting in special pain when the lateral side of the little toe is pressed. The main thing is to reduce the chronic wear and tear and improve the bad habits, but also can be used externally diclofenac diethylamide cream and so on. 2. Inguinitis: when the little toe is infected due to trauma and other reasons, and there is inguinitis causing edema around the nail groove and localized pus, the pressure on the outer side of the little toe may also cause pain. Local povidone-iodine disinfection and ichthyol ointment are applied to the affected area, and if there is abscess, consult a doctor in time for incision and drainage. 3. Trauma: Trauma causes soft tissue contusion of the little toe, resulting in local bleeding and edema, and pain can also be caused when pressing the lateral side of the little toe. If it is just a simple soft tissue contusion, generally it is cold compress first, then hot compress, oral diclofenac sodium extended-release tablets and other drugs to relieve pain. If there is a fracture, according to the situation, the choice of plaster immobilization or surgical fracture reduction and immobilization treatment. There are other causes of pain on the outside of the little toe, if rest does not relieve, it is recommended to consult a doctor, follow the doctor’s instructions for further examination, with the help of the doctor to clarify the cause, and targeted treatment or therapy. The above drugs are for reference only, the specific dosage should follow the doctor’s instructions.