Women with endometriosis causing infertility can see if their mothers and sisters have also suffered from this disease, and most women with this disease will find that they have relatives with the same condition. Conversely, if you have a relative with endometriosis infertility, you should pay attention to prevention. Normally, the endometrium covers the body of the uterus, but if the endometrium grows in other parts of the body due to certain factors, it can become endometriosis. Patients with endometriosis often suffer from menstrual disorders; lower abdominal discomfort, lumbago during menstruation, a feeling of swelling in the lower abdomen, and urgent and frequent urination during menstruation. Endometriosis also causes painful intercourse and affects sex life. Endometriosis often causes infertility due to pelvic masses, adhesions, poor follicular development or ovulation disorders caused by the lesions. Studies have found that endometriosis has a significant genetic predisposition, and women whose mothers or sisters have endometriosis are seven times more likely to get the disease than the general population. Therefore, women whose mothers or sisters have severe menstrual pain or are suspected of having endometriosis should take the initiative to get checked to facilitate early detection and to have a head start on treatment. If they are suffering from endometriosis, they should follow the doctor’s instructions and return for regular visits or check-ups. The causes of infertility due to endometriosis are: 1. autoimmunity and infertility: elevated anti-ovarian antibodies can affect ovulation and luteal insufficiency, and elevated anti-endometrial antibodies can affect endometrial changes that are detrimental to the implantation of pregnant eggs. 2. hyperprolactinemia: endometriosis is often combined with elevated lactation and PRL, which can affect ovarian function and lead to non-ovulation. 3. Excessive amount of ascites leads to infertility: Increased macrophages and lymphocytes in ascites of those suffering from endometriosis, increased acid phosphatase in ascites, and macrophages phagocytosis of sperm affect conception. In addition, when macrophages meet with antigenic substances, such as inflammatory substances and refluxed menstrual blood, they accelerate division and multiplication and have a direct cytotoxic effect on sperm and eggs, thus interfering with pregnancy.