Atrophic gastritis with enterocolitis does not necessarily require long-term medication, which can range from a few days to a few weeks. At present, there is no medication for atrophic gastritis that can reverse it, and the main treatments are symptomatic treatment, causative treatment, and regular review. 1. Symptomatic treatment: the duration of medication varies depending on whether the symptoms are relieved or not. If accompanied by acid reflux, heartburn can be given omeprazole, rabeprazole and other drugs; if accompanied by belching (hiccups), nausea can be given compound digestive enzymes, mitomycin pancreatic enzyme tablets and other drugs; if accompanied by hiccups, abdominal distension can be given mosapride, domperidone and other drugs. 2. Treatment: If there is Helicobacter pylori infection, it is necessary to give gastric triple or gastric quadruple medication, usually for about two weeks, according to the doctor’s instructions. 3. Regular checkups: Usually, gastroscopy is repeated once every six months to one year, and the interval can be extended if there is no obvious change. For the medication and duration of atrophic gastritis with intestinalization, it is recommended to consult a doctor.