Chromosome 22 trisomy is a rare chromosomal disorder that occurs with both spouses.
Normally, there are 23 pairs of 46 chromosomes in the body, one from the father and one from the mother, and when chromosome 22 trisomy is present in the body, it is a chromosomal abnormality.
The cause of chromosome 22 trisomy may be related to family history, smoking and drinking by husband and wife, consanguineous marriages, medication or viral infections in the early stages of pregnancy by the woman, and chemical work by either husband or wife, as well as some unclear etiologic factors.
As the disease is caused by permanent changes in chromosomes, there is no specific treatment that can cure it, and it can be detected during pregnancy to terminate the pregnancy.