Generalized numbness during sleep may be related to physiological factors, or it may be caused by autonomic dysfunction, cervical spondylosis, cerebrovascular disease and other reasons. 1. Physiological factors: such as respiratory alkalosis caused by over-excitement, excessive anxiety, tension and other psychological factors, may lead to generalized numbness in sleep. 2. Autonomic dysfunction: autonomic nervous system disorders or dysregulation may cause generalized numbness in sleep, which may be accompanied by dizziness, headache, chest tightness and other manifestations. 3. Cervical spondylosis: Especially in patients with cervical spinal stenosis or cervical disc herniation, if they keep improper sleeping posture for a long time, it will easily lead to local nerve compression, which may cause generalized numbness in bed, accompanied by neck and shoulder pain, dizziness and other manifestations. 4. Cerebrovascular disease: common in transient ischemic attack, cerebral hemorrhage, cerebral infarction and other diseases, due to local cerebral ischemia or hemorrhage, resulting in damage to the cerebral nerves, induced brain dysfunction, which may cause numbness in the whole body while sleeping, and may be accompanied by speech disorders, swallowing difficulties and other manifestations. Generalized numbness in sleep may also be caused by other reasons, if the symptoms continue to be unable to relieve, or frequent recurrence, it is recommended to consult a doctor as soon as possible, after clarifying the cause of the disease, and be guided by the doctor to carry out the treatment.