Other diseases can also cause bladder roughness, such as acute and chronic bladder infections or long-term irritation from stones, which can cause unsmooth and rough bladder walls. Therefore, tumors can cause bladder wall roughness, but bladder wall roughness is not necessarily a tumor. Tumors in the bladder can cause acute edema of the bladder mucosa or mucosal destruction, and if there are peripheral satellite foci, they can cause the mucosal surface to be unsmooth, which can be found to be grosser on imaging, and at the same time, imaging can reveal occupying changes that protrude above the mucosa, which requires further cystoscopy. Under direct cystoscopy, the local mucosa can be directly observed for atypical hyperplasia or abnormal mucosal lesions, and cystoscopy can also exclude grossness caused by other diseases, such as local infections or stones causing local mucosal grossness.