Dry and wrinkled skin under the eyes needs to be treated according to the cause of the symptoms, usually using medication, common causes include scaly blepharitis, contact blepharitis. 1. Scaly blepharitis: Scaly blepharitis is a mildly infected skin disease due to the high secretion of oil in the skin at the eyelid margin, resulting in sebum overflow, manifesting itself as a symptom of congestion and redness at the eyelid margin, and scaling, dryness, swelling, and wrinkling on the surface of the skin under the eyes. The eyelid margins can be cleaned with topical saline or 3% boric acid solution, and antibiotic ointment, such as fusidic acid cream, can be applied at the same time. 2. Contact blepharodermatitis: allergy-prone people, when the skin under the eyes comes into contact with certain allergens, such as eye creams, cosmetics, etc. may trigger contact blepharodermatitis, which manifests itself as itchy, burning sensation, erythema, pimples, blisters, dryness, wrinkles and other symptoms of the eyelids or the skin near the eyelids. It is necessary to avoid further contact with allergenic substances, can be used topically with topical glucocorticoid creams, such as Dinaid cream, hydrocortisone butyrate cream, etc., and severe symptoms can be combined with oral antihistamines, such as chlortetracycline, cetirizine and so on. All of the above drugs have adverse reactions and are recommended to be used under medical supervision. Dry and wrinkled skin under the eyes may also have other causes, it is recommended to go to the hospital in a timely manner to improve the examination, to clarify the cause of the disease to give targeted treatment.