It is not possible to have only one shot of HPV vaccine, generally speaking, HPV vaccine should be given three shots. If a patient does not get enough vaccine, the body does not produce effective antibodies and thus cannot prevent HPV infection well. HPV vaccine can prevent HPV infection and its resulting diseases such as genital warts, cervical precancerous lesions and cervical cancer. Patients should pay attention to the age of vaccination, there are different types of HPV vaccines on the market, and the appropriate age is different, such as the nine-valent vaccine for the appropriate age of 16 to 26 years old, quadrivalent for 9 to 45 years old, bivalent for 9 to 45 years old. In addition, patients should pay attention to the HPV vaccine, menstruation, pregnancy, breastfeeding women should not be vaccinated with HPV vaccine. After HPV vaccination, local reactions such as redness, swelling, heat and pain should be concerned. The vaccination needs to be done under the guidance of a professional doctor, and you can consult a doctor at any time if you have any uncomfortable symptoms.