Joint pain after drinking should be considered as an attack of gouty arthritis. Gout is a disorder of purine metabolism and impaired uric acid excretion that causes an increase in uric acid in the blood. Since wine contains a large amount of purine substances, it is easy to have joint pain symptoms due to increased blood uric acid after drinking. Its treatment: The first one, mainly general treatment, includes regulation of diet, control of total calorie intake and restriction of high purine foods. Such as heart, liver, kidney, brain, fish and shrimp, seafood and meat products. Among them, alcohol consumption is strictly prohibited, including beer containing large amounts of purines, preventing overweight and obesity, increasing uric acid excretion should drink more water, above two liters per day, not using drugs that inhibit uric acid excretion, such as thiazide diuretics, avoiding triggering factors and actively treating related diseases. The second one, mainly the treatment of acute gouty arthritis. It includes, bed rest, avoiding weight-bearing on the involved joints, giving colchicine quickly, and the earlier the treatment, the better the effect. Anti-inflammatory and analgesic drugs, such as ibuprofen and diclofenac, can also be taken.