“Probiotics have a therapeutic effect on gout”, this statement is unscientific and not true. Gout is a purine metabolism disorder caused by chronic metabolic diseases, daily life can be strict purine dietary control, reasonable exercise to regulate the level of uric acid, but also under the guidance of the doctor reasonable use of medication to control the occurrence of gout, such as stabilization to promote uric acid excretion, reduce uric acid production of medication, such as phenylbromarone, febuxostat, and so on. In addition to the conventional above treatments, microbial agents such as probiotics are increasingly used in hyperuricemia and gout, such as Lactobacillus, Clostridium casei and other probiotics. Probiotics are beneficial to enhance the ability of the intestinal tract to process uric acid and promote uric acid excretion, which may play a certain role in lowering uric acid, but probiotics have no therapeutic effect on gout. Gout patients can go to the regular hospital rheumatology and immunology department and other related departments for detailed consultation, and follow the doctor’s instructions for standardized treatment.