Clindamycin and cephalosporin are not better, and can be chosen based on different antibacterial spectrums and different diseases treated. 1. Clindamycin: belongs to the semi-synthetic lincomycin derivatives, used for the treatment of anaerobic bacteria and gram-positive bacteria caused by a variety of infectious diseases, such as tonsillitis, suppurative otitis media, acute bronchitis, pneumonia, lung abscess, skin and soft tissue infections, osteomyelitis, abdominal infections, pelvic infections, and sepsis. It should be noted that it is prohibited for those who are allergic to clindamycin, and should be used with caution in pregnant women, lactating women and children under 4 years of age, as well as those with impaired hepatic or renal function. 2. Cephalosporins: broad-spectrum antibiotics, can destroy the cell wall of bacteria, sterilization during the reproductive phase, almost no toxicity to humans, mainly used for treatment of drug-resistant Staphylococcus aureus and some gram-negative bacilli caused by serious infections, such as lung infections, urinary tract infections, sepsis, meningitis and endocarditis, etc., the application of which should pay attention to allergic reactions, and occasional anaphylactic shock and so on. Different drugs can not be compared, it is recommended that patients need clindamycin and cephalosporin, should be applied in accordance with the doctor’s instructions, do not blindly use their own medication, so as not to delay or aggravate the condition.