Stage II colon cancer means that the tumor has broken through the intrinsic muscular layer and reached the subplasma layer or has broken through the plasma layer and invaded the adjacent organs. However, during the surgery, the tumor can be completely removed without cancer residue and no metastasis in the surrounding lymph nodes, and the cure rate is over 80%, that is, the five-year survival rate is over 80%. However, after surgery, chemotherapy should be strictly administered, and a six-month course of treatment is routinely given, usually once every three weeks, with a one-week interval, and commonly used chemotherapy regimens include capecitabine and oxaliplatin. After the surgery, patients should come to the hospital every three months for a review of their CEA levels, and they should have annual colonoscopies to understand the lesions inside the colon.