Acute pharyngitis, acute tonsillitis, acute epiglottitis, malignant tumor of tonsil, laryngeal cancer, etc. can cause frequent sore throat, which can be disposed of by medication and surgery according to different causes. 1. Acute pharyngitis: people with decreased resistance often experience acute pharyngitis attacks under the stimulation of external factors, and those with severe symptoms can use acetaminophen, ibuprofen and other medications to reduce pain, and at the same time use penicillin, azithromycin, cefaclor and other medications for the treatment of anti-infection against the pathogenic bacteria. 2. Acute tonsillitis: mostly caused by bacterial infection, need anti-infection treatment, preferred penicillin or cephalosporin antibiotic drug treatment. 3. Acute epiglottitis: mild cases can be treated with antibiotics, severe cases need to add glucocorticoid drugs, treatment and prevention of epiglottis, aryepiglottis folds and other edema, anti-inflammatory, anti-allergy, anti-shock. If there is local abscess formation, incision should be made to drain the pus. 4. malignant tumor of tonsil: chemical drugs of cisplatin and carboplatin can be used for treatment. Tonsil lesion excision surgery and radiotherapy can also be used for treatment, and Tramadol and oxycodone can be used to relieve the symptoms if the pain is obvious. 5. Laryngeal cancer: Cisplatin, docetaxel, paclitaxel and other chemical drugs can be used for treatment. Cetuximab and other drugs can also be used for targeted therapy. Early laryngeal cancer can be treated with endoscopic surgery, local radiotherapy, etc. Those with obvious pain can use morphine, gabapentin and other drugs to ease the discomfort. If sore throat occurs, it is recommended to go to the hospital in time, after clear diagnosis, follow the doctor’s instructions to standardize the treatment.