Perianal itching is related to certain diseases, medications, and lifestyle. 1. Diseases: Perianal itching accompanied by bleeding, pain and other symptoms, considering hemorrhoids, anal fissure and other causes. Perianal itch accompanied by perianal pus, swelling and pain, considering the anal fistula, perianal abscess caused. Itchy perianal accompanied by abdominal pain, loss of appetite and other symptoms, considered pinworm disease. 2. Drugs: colchicine, tetracycline, neomycin, local anesthetics and other drugs, may cause perianal itching. 3. Lifestyle: the use of irritating shower gel, there are wet wipes to wipe the perianal area with force, unclean sex history, etc. may cause perianal itching. Perianal itch, it is recommended that patients go to the hospital to identify the causes, give appropriate treatment to avoid aggravation of the condition.