Hiccups in the clinic refers to hiccups, the sudden appearance of hiccups quickly stop the method of general therapy such as breath-holding method, closure therapy, external diaphragm pacemaker therapy, drug therapy such as baclofen and so on. 1. General therapy: breath-holding method after inhalation is mostly used for mental stimulation and eating too fast triggered by the double ball pressure method can be used for epigastric surgery, but high myopia, glaucoma patients should not be used, as well as pressure on the supraorbital nerve method, carotid sinus compression therapy, foot therapy, water breath-holding method, it is strictly prohibited to bilateral simultaneous compression of the carotid sinus, cardio-cerebral vascular disease is prohibited to contain water breath-holding method. 2. Closure therapy: nerve block therapy to unilateral appropriate, strict control of drug concentration and dose, and cervical spine transverse process side closure therapy. 3. extracorporeal diaphragmatic pacemaker therapy: it can be used for the treatment of persistent hiccups. 4. 4. medication: actively correct electrolyte disorders, can use muscle relaxants such as baclofen, antipsychotics such as haloperidol, antidepressants such as amitriptyline, central excitatory drugs such as niclosamide, calcium antagonists such as nifedipine, etc., but also can be used to use anesthesia, anticholinergics, antiepileptics, antiemetics and so on. Suddenly appeared eruption, need to timely examination, follow the doctor’s instructions standardized treatment, so as not to delay the condition.