The facial muscle spasm is an intermittent involuntary clonic twitching or painless tonicity of one side of the face, and the original symptoms may be aggravated by exertion or mental stress. The treatment of facial muscle spasm includes oral medication, local injection of botulinum toxin type A, surgery, etc. 1, oral medication: for patients with mild symptoms at the beginning of facial muscle spasm, sedatives and antiepileptic drugs can be used, commonly used are carbamazepine, oxcarbazepine, etc., alternative drugs are baclofen, gabapentin, etc. 2, local injection of botulinum toxin type A: if oral medication is ineffective or the symptoms are relatively heavy If oral medication does not work or if the symptoms are relatively severe, injections of botulinum toxin type A can be considered. The common adverse effects are short-term eyelid drooping, blurred vision, salivation, etc., which will disappear after a few days; 3. Surgical treatment: When local injection of botulinum toxin type A is not effective, surgical treatment such as peripheral neurectomy or facial nerve microvascular decompression can be used. Most patients with facial muscle spasm have a better prognosis after active treatment. In general, we should pay attention to relaxation, avoid excessive anxiety and tension, and avoid overexertion to avoid aggravation of symptoms.