The length of self-healing of esophageal mucosal injury varies from 7-15 days, and the specific length of self-healing is related to the patient’s disease type, treatment, and care measures. In clinical medicine, esophageal mucosal injury can be divided into 3 major types, namely mild, moderate and severe, according to the degree of disease. For patients with mild or moderate esophageal mucosal injury, antibiotics, gastrointestinal mucosal protective agents, proton pump inhibitors and other types of drugs can be used to accelerate the healing and repair of damaged tissues, such as ciprofloxacin, gastrin, omeprazole and so on. For patients with severe disease, surgical treatment and medication should be given according to the actual disease condition for comprehensive treatment. Good daily living and dietary care measures also play a positive role in accelerating the self-healing of mucosal damaged tissues, such as a light diet, adequate regular rest and relaxation and optimism.