Patients with lupus erythematosus are advised not to eat seafood during the acute flare-up period, while they can eat seafood in moderation during the stabilization period. Most of the seafood is high protein food, and when consumed by Lupus patients during the acute flare-up period, it will increase the risk of allergy, aggravate the condition, and bring extra harm to the body. However, if patients with lupus erythematosus consume seafood appropriately during the stabilization period, it can not only replenish energy for the body, but also replenish vitamins, proteins and other nutrients, which is conducive to the maintenance of health. However, it is necessary to pay attention to the moderate amount of intake, so as to avoid excessive consumption of seafood at one time, which may lead to abdominal pain, diarrhea and other adverse reactions. Lupus patients are advised to follow the doctor’s instructions on diet and pay attention to the nutritional balance.