Parkinson’s disease is a common neurological disorder that mainly affects middle-aged and elderly people, with approximately 30-40% of patients having depressive symptoms. Parkinson’s disease and Parkinson’s syndrome are not the same thing. Parkinson’s disease originates from degeneration of the substantia nigra and substantia nigra striata of the brain, while Parkinson’s syndrome is secondary to infection, poisoning and cerebrovascular disease, and patients develop clinical manifestations similar to Parkinson’s disease. In addition to primary Parkinson’s disease, the high number of cerebrovascular patients, environmental pollution and exposure to certain heavy metals and chemicals, traumatic brain injury caused by car accidents, gas poisoning and other accidental injuries are the main reasons for the increase in Parkinson’s patients. The most typical symptom of Parkinson’s disease is trembling. Patients’ symptoms are generally mild at first, and may only be stiff facial expressions, slow movements, and hand tremors …… These manifestations are often mistaken as normal aging of body functions and are not given enough attention. The survey shows that nearly half of Parkinson’s patients are “late” to the clinic, and many patients are diagnosed with the disease when it is already in the late stages. Experts remind the elderly that hand tremors and muscle stiffness are signs of Parkinson’s disease, and if hand tremors occur at rest, and the degree is increasing, and accompanied by reduced movement, you should promptly go to the hospital for diagnosis and treatment. Signs help to predict the disease In general, patients’ symptoms often appear slowly and unknowingly, and many patients cannot even recall the exact time of onset, so it is difficult to predict. In the early stages, patients often feel weak and have some difficulty moving, and the first site is usually in one hand or upper arm, such as walking without swinging the arm. Some patients’ early symptoms may manifest as numbness in the neck and arms, while others present with low back pain, both of which are often diagnosed as cervical or lumbar spondylosis. In addition, the initial symptoms of most Parkinson’s patients are unilateral limb weakness and shuffling when walking. These patients are easily misdiagnosed as having a stroke when they go to hospitals, especially some primary care hospitals, for examination. Other patients with dull facial expressions are misdiagnosed as Alzheimer’s disease or depression as a result. Therefore, if the above-mentioned early symptoms appear, especially in elderly people over 55 years old, they should be alerted to Parkinson’s disease and should be examined at a regular hospital with a Parkinson’s disease specialty or neurology department. Parkinson’s disease can be controlled Where the cause can be clearly identified is Parkinson’s syndrome, failure to find the cause is Parkinson’s disease. For the treatment of Parkinson’s disease, there are mainly drugs, surgery, genes, brain cell transplantation and other methods, among which drug therapy is the most mature and most used treatment, including neuroprosthetic drugs.