Parkinson’s disease is a disorder in which a specific area within the brain (substantia nigra) degenerates, resulting in the absence of dopaminergic neurons and therefore a decrease in dopamine secretion. When dopamine production is reduced in the brain, the body’s motor function becomes impaired. The most common symptom of Parkinson’s disease is trembling of the limbs, head, tongue, etc., or “shivering” as the people call it. In addition to tremors, Parkinson’s disease symptoms are actually very complex. In the early stages of the disease, some patients only show symptoms such as depression, unhappiness, often treated as “depression”; some patients in the early stages of the disease only show difficulty in turning over, walking, both shoulders or waist sinking, walking slowly, afraid to walk fast, lower limbs dragging, gradually small gait, starting difficulties, and only in the late stages of the hand, or arms, legs and other limbs of the stationary The tremors of the hands, arms, legs and other limbs appear at a later stage. Some patients have a reduced sense of smell, or changes in speech sounds, such as a smaller, thinner voice; some patients feel that limb movement is laborious, stiff or only show weakness; there are also elderly patients show increased drooling. In the later stages of Parkinson’s, some patients may experience dry stools, difficulty in relieving themselves, sweating and feeling oily on their faces; others may have difficulty sleeping or wake up easily. As long as the symptoms of “tremor” can be identified as Parkinson’s disease? The symptoms of tremor do not necessarily mean Parkinson’s disease. The first thing to think about is whether the patient has Parkinson’s disease, but in fact there are many diseases that can cause “tremors”. 1, combined with indifference to expression, monotonous language, and reduced voluntary movement should be distinguished from depression: generally coexist with Parkinson’s disease, but The first is the absence of muscle tonicity and tremor in depression, and experimental treatment with antidepressant drugs can help to differentiate; 2, to be distinguished from idiopathic tremor: idiopathic tremor has an early onset, postural or action tremor, such as hand tremor when carrying a bowl, taking a glass of water and pouring, head nodding or shaking, mostly aggravated by tension and excitement; there is no muscle tonicity and motor retardation, one third have a family history, and tremor is significantly reduced by drinking alcohol or taking insulin. 3, to be distinguished from the tremor secondary to drugs, stroke, poisoning, infection, etc. and genetic diseases of the nervous system, degenerative diseases appear.