Uric acid nephropathy is caused by hyperuricemia resulting from decreased renal excretion of uric acid and/or increased production of urate. Kidney damage caused by hyperuric acid includes acute hyperuricemia nephropathy, chronic hyperuricemia nephropathy and kidney stones. 1. Acute hyperuricemia nephropathy: it is an acute oliguric kidney injury caused by a large number of urate crystals deposited in renal tubules. It is most common in patients with malignant tumors and usually occurs within 1~2 days of chemotherapy. 2. Chronic hyperuricemia nephropathy: long-term hyperuricemia, increased excretion of uric acid, causing renal tubular interstitial injury or formation of renal stones, but also uric acid crystals may cause a series of inflammatory reactions, leading to pre-glomerular arteriolar lesions, renal inflammation, and renin-angiotensin system and cyclo-oxygenase-2 activation, thereby damaging the kidneys. 3. Kidney stones: due to insufficient solubility of uric acid in the urine, uric acid precipitates in the collecting ducts and stones are formed. People with hyperuricemia are prone to uric acid nephrolithiasis, which causes damage to the kidneys. If patients find uric acid nephropathy, it is recommended to go to regular hospitals in time, improve the examination to clarify the cause of the disease, and then give targeted treatment or treatment under the guidance of the doctor.