White flakes of peeling skin on the hands and feet, painless and itchy, considered related to herpes sweat, tinea cruris, exfoliative keratolysis, vitiligo and other factors. 1. herpes sweat: herpes sweat pathogenesis is not yet completely clear, considered with personal factors, mental psychological factors, genetic, environmental, disease and other factors, can occur in the hands and feet, resulting in the local appearance of clusters of blisters, blisters rupture can be caused by peeling, with or without pain and itching. 2. Tinea versicolor: Tinea versicolor is caused by fungal infections, such as dry tinea versicolor, which may lead to dry, flaky hands and feet. 3. Exfoliative Keratolysis: Exfoliative Keratolysis, which may occur in more than one family, is an exfoliative dermatosis that can occur on the hands and feet, resulting in localized circular erythema with white peeling in the center. 4. Vitiligo: Some studies have suggested that vitiligo is related to autoimmune diseases, psychoneurological factors, genetics and other factors. The area of skin damage, color loss, whitening, there may be flakes of skin off. In addition to this, vitamin deficiency, contact dermatitis and other diseases may also lead to peeling skin on hands and feet. It is recommended to pay attention to the care of the skin, do not scratch the irritation, and if necessary, go to the hospital dermatology department to find the cause.