Domestic thirteen-valent pneumococcal vaccine can be used to prevent thirteen serotypes of pneumococcal infections, thus greatly reducing the incidence of bacterial pneumonia. Domestic 13-valent Pneumovax vaccine can be used to prevent pneumonia caused by 13 serotypes of pneumococcal infections: 1, 3, 4, 5, 6A, 6B, 7F, 9V, 14, 18C, 19A, 19F, 23F, and cannot prevent infections caused by other serotypes of bacteria. The domestic 13-valent pneumonia vaccine can stimulate the body to produce an immune response after vaccination, and when the body is re-exposed to the above pathogens, it can rapidly produce an immune response and generate a large number of corresponding antibodies to prevent the occurrence of infection. Common adverse reactions to the 13-valent pneumonia vaccine include muscle pain at the injection site, swelling, redness, fatigue, headache and fever, etc. Less common adverse reactions include arthralgia, vomiting and diarrhea, which usually subside after a few days. If serious adverse reactions occur, prompt medical attention is recommended.