Gallstones can usually be detected by ultrasound, but smaller stones or stones that have fallen into the bile ducts may be negative. The first choice of auxiliary examination of gallstones is color ultrasound, compared with other auxiliary means of examination, such as CT, color ultrasound on the stone of higher sensitivity, but also has the advantages of easy to operate, low price, no radiation and so on. In addition, color ultrasound can clarify whether the wall of the gallbladder is thickened, whether there is cholestasis, etc., which has a high diagnostic value in the diagnosis of gallstone disease. Although the diagnostic value of color ultrasound is high, when the stones are small or have fallen into the common bile duct and other parts of the gallbladder, the judgment may be negative, and further CT and other auxiliary examinations are needed. In addition, it should be noted that before the color ultrasound examination, should pay attention to fasting for 6~8 hours, to avoid eating caused by the gallbladder contraction and bile excretion to affect the results of the examination. If you have gallstones, you should consult a doctor in time and take ultrasound and other auxiliary tests under the doctor’s guidance, which will help you to clarify your condition and treat it in a timely manner.