During treatment with cephalosporins, some patients may experience delayed allergic reactions, which may occur as a rash or chills or fever some time after the drug has been administered, or they may not be allergic the first time they use cephalosporins and only develop allergic symptoms the second time they use them. Most of these allergic symptoms are similar to acute allergic reactions and can include itching and rash of the skin, or bronchospasm, allergic asthma, as well as chills and fever. In severe cases, there may even be anaphylactic shock manifestations such as decreased blood pressure and accelerated heart rate. Therefore, the drug should be discontinued in time, and appropriate anti-allergic and other resuscitation treatments should be given, and the use of cephalosporins should be avoided in the future, including other β-lactam drugs, such as amoxicillin, etc. It is also best to use them with caution to prevent cross-allergic phenomena.