Whether to use ultrafiltration therapy or diuretic drugs such as furosemide for edema complicated by membranous nephropathy needs to be judged comprehensively according to the patient’s edema, renal function, indications and contraindications for drugs or treatment, and cannot be generalized. Furosemide treatment is suitable for those who have obvious edema and cannot reduce the swelling after using hormones and restricting water and sodium intake. However, it is contraindicated for those with hyponatremia, hypokalemia, etc. It should also be used with caution for those with hyperuricemia, gout, pancreatitis, lupus erythematosus and other diseases. Ultrafiltration therapy is also known as dialysis therapy. It is suitable for those who have serious damage to renal function, with blood creatinine above 707μmoI/L, and those who have electrolyte or acid-base balance disorders such as severe hyperkalemia, acidosis, etc., which are not effective in drug intervention, and those who have edema, which is not effective in drug intervention, and complicated with intractable cardiac failure, etc. It can be used. Ultrafiltration is contraindicated in cases of active bleeding or high risk of active bleeding, coagulation disorders, shock, and localized skin infections. The specific choice of treatment for patients with membranous nephropathy requires comprehensive judgment by clinicians, and it is recommended to go to the hospital in time and under the guidance of doctors.