The common causes of enlarged heart shadow are hypertension, coronary heart disease, heart valve disease, etc., which can be treated with medications such as valsartan and, if necessary, surgery. 1. Hypertension: Hypertension can lead to an increase in the afterload of the heart, resulting in the enlargement of the left ventricle. Imaging can reveal an enlarged heart shadow, and the treatment should be to control high blood pressure, and the commonly used medications include valsartan, amlodipine, etc., to avoid further enlargement of the heart. 2. Coronary artery disease: patients can have myocardial ischemia, long-term ischemia can also lead to myocardial hypertrophy, manifested as ischemic cardiomyopathy, aspirin, atorvastatin, isosorbide nitrate and other drugs should be given to improve the blood supply to the myocardium, and implantation of stents if necessary. 3. Heart valve disease: this kind of disease will cause hemodynamic disorder, the volume load of the heart increases, can also lead to heart enlargement. Early to reduce the cardiac load, commonly used drugs, including furosemide, etc., late surgical treatment to replace the valve. There are many other reasons for an enlarged heart, so it is important to find the cause of the disease and treat the primary disease with a clear diagnosis under the guidance of a physician.