Direct bilirubin 8.1 μmol/L is not very serious. Direct bilirubin, also known as conjugated bilirubin, is produced by the action of glucuronosyltransferase after indirect bilirubin enters the liver and is excreted through the biliary system and the kidneys. Direct bilirubin measurement helps in the diagnosis of diseases of the liver and biliary system. The normal range of direct bilirubin is 0-6.8 μmol/L. When the metabolic function of the liver is abnormal, direct bilirubin can be elevated, but it does not mean that there are irreversible organic lesions in the liver. Direct bilirubin of 8.1 μmol/L is higher than the normal range, but the degree of elevation is not large, so it is considered to be not too serious. The patient direct bilirubin 8.1μmol / L recommended adjusting the habits of life, monitoring for a period of time indicator changes, to clarify the cause of the disease, for timely treatment.