No spirit, people always feel tired mainly with long-term late night, excessive fatigue, anxiety and depression, diabetes, etc., as follows: 1, a long time to stay up late, excessive fatigue, resulting in sleep deprivation, the brain and the body can not get a good rest, will feel tired and weak, mental fatigue. Usually to develop good habits of life and work, try to go to bed early and get up early, you can exercise properly, learn to relax, do not often be in a state of tension, which over time can easily lead to memory loss, resistance to decline, etc. 2, anxiety, depression, the patient loves to think, depressed, not interested in the surrounding things, usually pay attention to communicate with family members and friends, can not be self-regulation can be in the guidance of the doctor orally Dailixin and other medications. 3, diabetic patients with markedly elevated blood glucose, unsatisfactory control, a large amount of glucose discharged from the urine resulting in fatigue, lethargy, polyphagia, polydipsia, etc., the need to monitor the blood glucose, a low-sugar diet, and active drug control.