Adhering to the prescription and fighting against tumor with “protracted war” malignant tumor is a difficult disease to be treated, no matter for Western medicine or Chinese medicine. From the current stage, malignant tumor is still a disease with great difficulty in treatment: it is insidious, difficult to be found early and eradicated by surgery; it progresses rapidly after the onset, difficult to be stopped by general means; the efficacy of some currently recognized treatments is still limited and the side effects are large; it is easy to recur and metastasize, difficult to be prevented and controlled; and it can break through the human body’s defense from both physical and mental aspects, completely disintegrating human resistance and will. It is also difficult to prevent and control. Therefore, from the patient’s point of view, once a person suffers from malignant tumor, it is like establishing a powerful opponent that is extremely difficult to overcome. From this point of view, most of the malignant tumors are difficult to win quickly, especially those patients who are found late, receive effective treatment late, and have poor physical constitution, they need to establish a tenacious and persistent confrontation faith in order to have more hope to overcome this disease. Compared to patients, clinicians especially need to establish such a correct concept that tumor is a disease that needs long-term prevention and treatment. Even if patients have good results through surgery and radiotherapy treatment, they still need to adhere to long-term medication, enhance anti-disease ability, prevent recurrence and resist metastasis so as to give patients the most effective guidance and support in long-term treatment. Sun’s prescriptions are often used in clinical medicine to support the positive and eliminate the evil together, and the legislation is mostly based on supporting the positive, just to ensure that the prescriptions are taken for a long time; and the idea of attacking and supplementing at the same time, preventing as the main and attacking as a supplement, improving the quality of survival of patients with advanced disease and long-term survival with tumors, makes Sun’s prescriptions can be adhered to by patients for 2-3 months or longer, as Chinese medicine says As Chinese medicine practitioners say, “the effect of the prescription should not be changed”, asking patients to take one dose of medicine for 2 days is the embodiment of the idea based on this “protracted war”. People-oriented, mobilize all anti-cancer forces One of the general factors that anti-tumor treatment needs to be persisted for a long time is “the weakness of the positive and the strength of the evil”. In the face of malignant tumors with strong and destructive power, the resistance of human body and will is relatively weak. Therefore, in order to fight against the evil of malignant tumor with my positive deficiency, we must mobilize and stimulate the power that can be fully utilized in our body to achieve this. From the discriminative point of view, human body and disease are a unity of contradiction, i.e., the cause of disease is attached to the human body and the human body struggles with it because of the disease. In this unity of contradictions, the focus and the core are “people” – as long as there is still a breath, the human body will struggle with disease; therefore, the struggle between the human body and disease is a struggle between you and me, a struggle between this and that. In this struggle, we must put people first in order to achieve ultimate victory. This reality, reflected in the theory of Chinese medicine, is the struggle between the righteousness and the evil, and the discriminatory unity of “supporting the righteousness” and “eliminating the evil”. It is emphasized that positive qi is the sum of all the anti-disease abilities in the body, as stated in Huang Di Nei Jing? As stated in the “Shanggu Tianzhen Lun”, the true meaning of “the righteousness exists within, and the evil cannot be interfered with” is “the harmonization of qi, blood, yin and yang, and mental health”, which includes both physical and mental aspects. To summarize, all factors that can strengthen the patient’s physical and resistance strength and make the spirit calm and smooth belong to the category of positive energy or support positive energy, while all factors that can fight against tumors belong to the category of eliminating evil. As a clinician, his duty is to mobilize and coordinate all the forces that can “support the righteousness” and “dispel the evil” to fight against tumors and eventually overcome them. In addition to the traditional drugs to support the righteous (such as strengthening the spleen and kidney, benefiting qi and nourishing yin, etc.) and dispel the evil (such as clearing heat and detoxifying the blood, activating blood stasis, softening and dispersing nodules, etc.), certain combinations of drugs are often seen, such as raw pu huang, blood Yu char, dahurica dahurica, Lu bifang, or dai ochre, chicken naijin, raw malt, or helianthus bark, nightshade, or licorice, fructus wheat, jujube, etc., which are actually used to dispel blood stasis and create new energy. Even subtle factors such as poor sleep, which may affect the patient’s physical recovery, and irritable sweating, which may affect the patient’s mood, are all within the scope of Sun’s attention and immediate response, reflecting Sun’s profound understanding of “if the righteousness exists within, the evil cannot dry up”. Harmonization of internal and external, unity in the fight against cancer Malignant tumor is both a localized lesion and a disease involving the whole body. If it can be detected early and eradicated by early surgery, its prognosis will be greatly improved, which reflects its characteristics of localized lesions; however, if it is detected late, misses the opportunity of surgery, or has recurrence or metastasis, it may involve many organs and systems of the whole body and affect their functions, and its prognosis will be significantly worse. On the other hand, Dr. Sun also noted that the human body is a very delicate and complex whole. Its complexity is reflected in the intricate relationship between the five internal organs, qi, blood and fluids; and its subtlety is reflected in the coordination and harmonious coexistence of all components of the human body, which constitute the material basis for the normal function of the human body. Therefore, the complexity of both human and malignant tumor determines the complexity of treatment. According to Sun, when treating the contradiction between the two, it must be dealt with reasonably according to the actual situation, and the key point is to coordinate two pairs of relationships, one of which is the relationship between helping the positive and eliminating the evil, and the other is the mutual relationship between the functions of the internal organs in the body. One is the relationship between helping the righteous and eliminating the evil, and the other is the interrelationship between the functions of the internal organs. The meaning of “discernment” is: supporting the positive is the basis of dispelling the evil, dispelling the evil is the purpose of supporting the positive; supporting the positive focuses on consolidating the internal, dispelling the evil to defend against external evil as the goal; supporting the positive emphasizes the role of internal factors, dispelling the evil emphasizes the role of external factors. One main internal and one main external, the two should neither be confused nor replaced by each other. The ultimate goal of helping the positive and eliminating the evil is the same and unified, that is to preserve life and overcome tumors. Therefore, in his prescriptions, Dr. Sun always uses the same medicine to help the righteous and eliminate the evil, but most of the time, the righteous is the mainstay and the evil is the supplement, so that the two do not replace each other and coexist harmoniously on one side, and the efficacy of the treatment is doubled with half the effort and the patient benefits. As for the interrelationship between the five internal organs and the six internal organs, according to the traditional saying, “they are mutually dependent on each other”, but Sun believes that the essence is also the unity of discernment: the mutual “gram” between the five internal organs and the six internal organs is the manifestation of their struggle; while the “life” is the manifestation of mutual dependence. Sheng” is the basis of interdependence and mutual transformation. The relationship of “Sheng” is the mainstream, and the purpose of “Gram” is to make the five internal organs and six internal organs more harmonious, so that they can function optimally. Since patients with advanced malignant tumors often have metastases or multiple organ damage, when dealing with these complicated situations, it is often necessary to consider the coordination of the functions of the five internal organs and the six internal organs to make them conform to normal physiological requirements, so as to ensure the basic needs of human life activities. For example, in addition to pulmonary symptoms and signs, patients with advanced lung cancer may suffer from abdominal distension, poor appetite and loose stools due to loss of spleen qi and loss of transportation. Therefore, according to the needs of the condition, we must give appropriate treatment to strengthen the spleen and benefit the qi, clear the heat and stomach, benefit the kidney and nourish the qi, dredge the liver and activate the blood, drain the heat and open the stool, and nourish the heart and spleen to promote the coordination of the functions of the organs, which will be conducive to the continuation of the normal life activities of the human body and thus to the recovery of the lung disease itself. The spleen and kidneys play an important role in the five viscera and six internal organs: the kidneys are the organs of true water and true fire, and true water nourishes liver wood to produce heart fire, and true fire supports spleen earth to produce lung gold, so the kidneys are used to nourish yin and warm yang. Without the nourishment of food and water, people will not even be able to support themselves for a few days, so it is clear that the spleen and kidney are the essence of the body’s vital energy. There is also a close relationship between the two that nourishes each other, that is, the spleen needs the warmth and promotion of the kidney yang, and the kidney yin and kidney qi also need to be constantly nourished by the water and grain essence transported by the spleen. Therefore, if the spleen and stomach are deficient, the biochemical source of qi and blood is lacking, both the spleen and kidney will be damaged, and the person’s ability to resist disease will be weakened. The treatise on the spleen and stomach has long recognized this point, and therefore says, “The sufficiency of vital energy is due to the spleen and stomach’s qi not being injured, and then it can nourish the vital energy; if the stomach’s qi is weak …… and the spleen and stomach’s qi is injured, and the vital energy cannot be filled. This is the cause of all diseases”. Zhang Jinyue further recognized the relationship between spleen and kidney deficiency and tumor, pointing out that “people with spleen and kidney deficiency and weakness and disorder have the disease of accumulation”, and summarized the corresponding treatment through practice, such as “where the treatment of choking and diaphragm, the spleen and kidney should be the main focus. The treatment of the spleen should be from warming, and the treatment of the kidneys should be from nourishing” and so on. Based on the experience of his predecessors and years of clinical research, Dr. Sun believes that nourishing the spleen and benefiting the kidneys and protecting the “essence of the successive heaven” is an effective way to regulate the physiological functions of the human body and improve the ability to resist diseases, and this method is often used clinically together with the corresponding antidote and anticancer drugs to support the righteousness and dispel the evil, with many good results. The “Spleen and Kidney Tonic Detoxification Formula” has shown incomparable superiority in both laboratory and clinical applications. Typical case Patient Xu, male, 48 years old. He came to our outpatient clinic in May 2005. The patient was 9 months postoperative for gastric cancer, pathological type: hypofractionated adenocarcinoma, IIIb, 6/21 lymph node metastasis, and 6 cycles of postoperative chemotherapy with Ai Heng + 5-fu + CF. Repeat CT revealed abdominal lymph node metastasis and ultrasound of superficial lymph nodes suggested multiple metastases in supraclavicular lymph nodes up to 1.4×0.4 cm, and is now treated with oral Siroda. The patient complained of epigastric pain, which was persistent and vague, aggravated after eating, accompanied by nausea, acid reflux, loss of appetite, and weakness, on examination: T 36.6℃, P 84 times/min, Bp 110/70mmHg. chronic disease appearance, mild anemia appearance, yellowish face, flat and soft abdomen, subxiphoid pressure pain (+), no rebound pain, liver and spleen were not palpable, no mobile turbid sounds, no edema in both lower limbs. The tongue is light red, with little coating and weak pulse. Auxiliary examination: blood routine: WBC 2.4×109/ L, N 65%, Hb 66g/L. Stool occult blood test (+). The diagnosis of Chinese medicine is due to deficiency of both spleen and kidney, deficiency of qi and yin, loss of harmony and descent of the stomach, and residual toxicity not yet cleared. The treatment should be to support the righteousness and eliminate the evil. The treatment should be to strengthen the spleen and kidney, benefit the qi and nourish the yin, harmonize the stomach and subdue the rebelliousness, anti-cancer and detoxify the toxin. Herbs: Astragalus membranaceus 30g, Radix Paeoniae Alba 15g, Radix Codonopsis Pilosulae 15g, Rhizoma Atractylodis Macrocephalae 15g, Poria Cocos 15g, Rhizoma Atractylodis Macrocephalae 10g, Rhizoma Polygonatum 15g, Rhizoma Polygonatum 5g, Rhizoma Polygonatum 10g, Rhizoma Phellodendron 10g, Rhizoma Gastrodiae 15g, Rhizoma Bupleurum 10g, Rhizoma Gastrodiae 15g, Rhizoma Polygonatum Vulgare 30g, Rhizoma Polygonatum 30g, Rhizoma Bupleurum 10g, Rhizoma Forskohlii 10g, Rhizoma Serpentis 15g. 10g, 15g of Serpent’s Tongue, 15g of Buddha’s Hand, 15g of Cao He Che, 10g of Sheng Cao. 1 dose every 2 days, divided into 2 doses. Subsequently, the above formula was treated with slight addition and subtraction with the evidence for more than 4 years, and the patient’s condition was stable. In February 2009, the abdominal CT and ultrasound of superficial lymph nodes were reexamined in our hospital, suggesting that the lesions were stable and the symptoms improved, and the patient continued to be treated with outpatient Chinese medicine in our hospital. Conclusion Malignant tumor is a difficult disease to treat. Through the combination of evidence and disease identification, Dr. Sun realized that the treatment of malignant tumor must be “human-centered, with the righteousness as the first priority”, therefore, based on helping the righteousness and eliminating the evil, emphasizing the important role of spleen and kidney in maintaining the righteousness, through regulating the spleen and kidney and protecting the “essence of successive heaven”. “The treatment process must adhere to the formula, fight against tumors with a “protracted war”, effectively improve the quality of survival of tumor patients, and achieve success in inhibiting tumor recurrence and metastasis, stabilizing and shrinking tumors, effectively improving the quality of life and prolonging survival. It is worth to further explore in depth to discover the universal rules of Chinese medicine to suppress tumor and prevent recurrence and metastasis for the benefit of tumor patients.