Urine protein 2 + suggests proteinuria, divided into physiological conditions and pathological conditions, physiological can generally be eliminated with the elimination of factors affecting the body’s physiological response and the recovery of renal function and disappear; pathological can not necessarily return to normal, need to be based on different causes of the selection of appropriate treatment options to minimize the urine protein. Physiological conditions: seen in strenuous exercise, fever, low-temperature stimulation, mental stress, sympathetic nervous excitement, etc., this proteinuria can be eliminated with the elimination of factors affecting the physiological response of the body and the recovery of renal function and disappearance; in addition, there is also a positional proteinuria, i.e., lying down when the urine protein negative, get up after activities or stand for a long time, urine protein positive, lying down after rest and negative. Pathological conditions: glomerular proteinuria and tubular proteinuria. When the quantitative amount of urinary protein > 3.5g/24h, it is called massive proteinuria, the most typical case is nephrotic syndrome, at this time, furosemide and other diuretics can be used to reduce swelling, and according to the different types of pathology, such as hormone and/or immunosuppressant selection of treatment. Tubular proteinuria can be seen in interstitial nephritis, pyelonephritis and other tubular interstitial lesions; certain antibiotics such as gentamicin, kanamycin, polymyxin, herbal medicines such as Aristolochia sinensis, Mucuna pruriens, and organic solvents such as benzene toxicity induced by drug intoxication. At this time should also be based on different causes to choose the appropriate treatment program. Urine protein 2 + should cause certain attention, the patient should go to the hospital for relevant examination, and under the guidance of the doctor active treatment, clear causes, as far as possible to make urine protein gradually return to normal.