People who drink too much alcohol can lead to pain in the bones, when people drink alcohol in the alcohol, in the liver under the action of the enzyme ethanol dehydrogenase rapidly decomposed into acetaldehyde. Acetaldehyde is a harmful substance to the body that dilates the capillaries causing increased permeability of the capillaries. Inflammatory mediators are deposited in the bones and skeletal muscles, such as bradykinin, leukotrienes, tumor necrosis factor, interleukin-6 and other inflammatory mediators, and pain in the bones occurs. Drinking too much alcohol on the basis of the original bone and joint disease, such as rheumatic bone disease, rheumatoid bone disease, gout disease, the original basic disease will be aggravated, the appearance of bone and bone pain is unusually pronounced and sensitive situation. After drinking too much alcohol, the ethanol in alcohol is converted into acetaldehyde, and ethanol is converted into acetic acid, which is an acidic substance that makes the bones sore and painful, so drinking too much alcohol will lead to bone pain.