Sore throat can be seen in acute laryngitis, reflux pharyngitis and other diseases. It is recommended that patients go to the hospital, clear causes for treatment, clinical according to different causes and symptoms often use amoxicillin, ampicillin, omeprazole and other drugs for treatment. 1. Acute laryngitis: laryngeal pain and hoarseness, pain aggravated by vocalization. The most important measure of treatment is vocal rest, no voice, less voice. Oral or injection of amoxicillin, ampicillin and other antibiotics, timely control of inflammation; vocal folds congestion and swelling significant addition of dexamethasone and other glucocorticoids. 2. Reflux pharyngolaryngitis: reflux of stomach contents can lead to throat pain, hoarseness and other symptoms. Acid-suppressing drugs such as omeprazole and other gastrointestinal power drugs such as mosapride can be used, and pharyngeal application of budesonide suspension nebulized inhalation to reduce the edema of the vocal folds and alleviate the inflammatory reaction. Oral sweet orange bingmei tablets and six god pill to improve the symptoms of sore throat. It is recommended that the patient go to the hospital in time to see a doctor, after clarifying the cause of the disease, standardized treatment. The above drugs should be used under the guidance of a physician to avoid adverse reactions.