The main sequelae of cranial opening are: 1, cranial defect: If the cranial defect is greater than 3 cm, cranial repair should be done, the time of cranial repair, in the absence of infection, the surgery can be performed 3 months after the injury; if the wound is infected, the surgery should be delayed to more than six months after the injury healing. 2, traumatic epilepsy: traumatic epilepsy is mainly the seizures caused by cranial injury, mainly by drug treatment If there is a clear limited lesion present, surgery can be performed to get rid of the cause. 3. post-traumatic brain injury syndrome: mainly manifested as headache, dizziness and autonomic dysfunction, treatment is mainly taken as comprehensive treatment means. 4. intelligent damage: after traumatic brain injury, patients are often accompanied by mental and intellectual impairment due to damage to brain nerve cells, treatment is mainly taken as early rehabilitation treatment.