Celiac disease refers to cervical columnar epithelial ectasia, severe cervical columnar epithelial ectasia for 10 years most will not be cancerous, a small number of cases may be cancerous, to pay attention to. Cervical columnar epithelial ectasia is a physiological phenomenon of cervical columnar epithelial ectasia, it is the columnar epithelial ectasia from the inner mouth of the cervical canal to the outer mouth of the cervical canal, usually there is no obvious clinical symptom, due to the columnar epithelium is relatively thin, it looks like vesiculation, so it used to be called celiac disease of the uterine cervix, but it is not a pathologic epithelial detachment and ulcerations, which is a kind of normal physiological change, usually it will not be cancerous. However, if cervical columnar epithelial ectasia is accompanied by HPV infection, attention should be paid to this situation, which may become cancerous, and active cooperation with the treatment is required. Severe celiac disease for 10 years usually should go to the hospital on time for review, pay attention to personal hygiene and sexual hygiene, reduce the number of sexual partners, eliminate bad sex.