HP positivity is usually considered to be a sign that the patient has a Helicobacter pylori infection. HP stands for Helicobacter pylori, and HP positivity often indicates the presence of H. pylori infection in the stomach. H. pylori is contagious and can be contracted through contact with saliva, vomit, or feces of an infected person. Common tests for H. pylori include non-invasive and invasive tests, such as carbon 13 and carbon 14 breath test, and invasive tests, such as rapid urease test, etc. The above tests can diagnose whether a patient is infected with H. pylori or not. H. pylori can damage the gastric mucosa, causing gastritis, gastric ulcer, duodenal ulcer, etc., and in serious cases, it can induce gastric cancer, so it should be diagnosed and treated early. Clinically, quadruple therapy is commonly used, which includes bismuth, proton pump inhibitor, and two kinds of antibiotics, such as omeprazole, amoxicillin, clarithromycin, and bismuth citrate potassium, and the course of treatment is usually 10-14 days. If patients are diagnosed with H. pylori infection, it is recommended to go to the hospital for standardized treatment in time to reduce the adverse effects of the disease.