Progress in the treatment of adrenoleukodystrophy abroad 1. Lorenzo oil can reduce very long chain fatty acids to normal within one month, but it is currently recommended only for asymptomatic patients after the age of 1 year. It is not effective in patients with existing neurological symptoms. Bone marrow transplantation reversed the pathological process in a patient with early neurological symptoms. It does not work well in patients who are already in the later stages of the disease at the time of detection.