Liver cancer patients are recommended to undergo surgical resection, radiotherapy, targeted therapy, etc. Hepatic encephalopathy is recommended to confirm and remove the causative factors, local nutritional support, drug therapy, and both of them are recommended to undergo liver transplantation when necessary. Hepatocellular carcinoma is a cancer with high incidence rate in China, and patients with hepatocellular carcinoma are generally recommended to take the comprehensive treatment with surgical resection as the main treatment, and the effect will be better when supplemented with comprehensive treatment after surgery. However, if patients are not suitable for surgical treatment, they can also choose radiotherapy, chemotherapy (cisplatin, fluorouracil, etc.), interventional therapy, targeted therapy (sorafenib, lenvatinib, etc.), etc., and liver transplantation is needed in serious cases. Hepatic encephalopathy requires comprehensive measures for treatment, mainly including: elimination of triggering factors, protein fasting, massive glucose infusion, enema or diarrhea to remove intestinal accumulation of food, blood or other nitrogenous substances, use of nitrogen-reducing drugs, such as potassium glutamate, sodium benzoate, etc., to correct the disorders of amino acid metabolism, and in severe cases, need to undergo liver transplantation. The above drugs should be used in a standardized and rational way under the guidance of professional physicians and pharmacists.