Frequent waking up in bed may be caused by physiological factors, vitamin D deficiency rickets, eczema, gastrointestinal diseases and other factors. 1. Physiological factors: the presence of noise around the time of sleep, high indoor temperature, wet diapers and other physiological factors can lead to frequent waking of the baby during sleep, no other clinical symptoms, eliminate the above reasons, can return to normal. 2. Vitamin D deficiency rickets: excessive lack of vitamin D in the baby’s body will affect the absorption of calcium, and the baby will wake up frequently during sleep, accompanied by crying and pillow baldness and other symptoms. 3. Eczema: may be related to genetic, external stimuli and other factors, can make the local skin red papules, accompanied by itching and erosion and other symptoms, will make the baby uncomfortable, will wake up frequently during sleep. 4. Gastrointestinal diseases: such as indigestion, intestinal teratology, etc., can cause abdominal distension and abdominal pain and other symptoms, which will make the baby wake up frequently during sleep, may also be accompanied by vomiting, diarrhea and other symptoms. Baby sleep frequently wake up, there may be other reasons, it is recommended to go to the hospital in time to improve the examination to clarify the cause of the disease, under the guidance of the doctor to give targeted treatment or treatment.