The pain produced by changing the medication for perianal abscess is related to the individual’s physical condition and the severity of the condition, and the exact degree of pain usually varies from person to person. Perianal abscess is an acute suppurative infectious disease that occurs around the anus, anal canal and rectum. Due to the abundance of nerve endings around the anus, once an abscess is formed around the anus, the stimulation of inflammation will produce painful symptoms. Pain is currently graded on a 10-point scale, and when the condition is relatively mild, the pain level is basically tolerable, around 1-3. Patients may experience increased pain during the first dressing change. Since the dressing change involves cleaning the wound and filling it with clean gauze, usually without anesthesia, the pain is about a 5-6 on a moderate scale, and may reach a 8-10 if the abscess symptoms are more severe. If the pain is more serious, patients can take pain medication such as ibuprofen and celecoxib to relieve the pain under the guidance of the doctor. It is recommended that patients strictly follow the doctor’s instructions to use medication, actively cooperate with the doctor’s treatment, if necessary, can also be through the warm water sitz bath or 1:5000 potassium permanganate solution sitz bath and so on to alleviate the condition.