Ultrasound suggestive of enhanced parenchymal echogenicity in both kidneys refers to a lesion in the intrinsic parenchyma of both kidneys. It is often indicative of acute or chronic kidney disease. Acute glomerulonephritis, chronic glomerulonephritis, nephrotic syndrome, hypertensive nephropathy, diabetic nephropathy, membranous nephropathy, crescentic nephropathy, etc. These renal diseases can lead to such changes on the ultrasound, and generally there will be diffuse renal parenchymal rebound enhancement on the ultrasound. In addition, kidney calcification may also appear as localized parenchymal enhancement. It is recommended to go to the hospital for further 24-hour urine protein quantification, blood sugar, blood pressure, urine microalbumin test and urine routine examination to clarify the condition. If it is suspected to be caused by nephritis, a kidney puncture should be done to clarify which type of nephritis is causing the problem. Therefore, the ultrasound indicates that both kidney parenchymal echogenicity is enhanced, and further examination is needed to exclude nephritis.