The causes of sudden awakening from sleep with palpitations are: 1, arrhythmia, tachyarrhythmic diseases may appear symptoms of panic, may be night palpitations, may be daytime palpitations, may be palpitations after activity, can line dynamic electrocardiogram to assist in the diagnosis. 2, ischemic heart disease, such as acute myocardial infarction, stable angina pectoris, mixed angina pectoris, worsening exertional angina pectoris and other coronary heart disease will also appear. Wake up during sleep palpitations. 3, heart failure, when there is left heart failure there will be tightness of breath, dyspnea, further progression of symptoms will appear at night paroxysmal dyspnea, there may be a sudden awakening at night panic symptoms. 4, certain cardiomyopathies may also appear this symptom. In short, there are many diseases that can cause this symptom, and it needs to be further clarified through relevant examinations.