White spots appear on the face after playing hyaluronic acid dissolving enzyme, the treatment is mainly based on the size of the white spots to choose different ways of treatment, including observation, drug treatment and surgical treatment. 1. Observation: the white spots appearing on the injection site may be related to skin damage or vitiligo, after the white spots appear, observe whether they fade away in a short period of time, if the white spots don’t fade away or increase in size, then you should go to the hospital in time for consultation. 2. medication: for the area continues to increase the white spots, it is necessary to immediately improve the Wood’s lamp examination and pathological examination to exclude vitiligo. After the diagnosis of vitiligo is clear, it is necessary to follow the doctor’s instructions to give glucocorticoid drugs (such as betamethasone) and calcium-modulated phosphatase inhibitors (such as pimecrolimus) treatment. 3. Surgical treatment: for vitiligo patients with stabilized white spots, autologous epidermal transplantation can also be taken in the case of aesthetic impact. If the white spots on the face do not subside within a short period of time after playing hyaluronic acid lysozyme, it is recommended to go to the hospital, under the guidance of the doctor for treatment.